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Major issues related to frailty and aging

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Among the various open questions raised by normal and pathological ageing, the Lc65+ cohort aims to contribute to answering the following:


Why do some individuals get frail but others remain robust until a very old age ?

What are the first manifestations of frailty? Can we detect frailty early ?

Is the frailty process perceived by older persons? Does frailty change their quality of life ?

Are there different ways to become frail? What parts do somatic and mental health disturbances play in the development of frailty ?

What factors influence the evolution of frailty and the development of its consequences? Are there modifiable factors that might help design interventions to prevent frailty and its consequences ?



Lc65+ study

The Lausanne cohort 65+ (Lc65+) study is a research platform that aims to gain new knowledge on frailty in the general population from the age of 65 years onwards. Manifestations of frailty, medical and psycho-social risk factors, and the effects of frailty on health, functional status, and use of health services are central to the research conducted in the Lc65+ project.